CVE-2021-42321: Microsoft Exchange Server Remote Code Execution Vulnerability
Actively exploited. At least one CVE in this advisory is listed in the CISA Known Exploited Vulnerabilities catalog — exploitation has been observed in the wild. Treat remediation as urgent.
An authenticated attacker could leverage improper validation in cmdlet arguments within Microsoft Exchange and perform remote code execution.
CSIRTS triage
- What
- The vulnerability allows an authenticated attacker to perform remote code execution due to improper validation.
- Who is affected
- Authenticated users of Microsoft Exchange Server are affected.
- Urgency
- Remediation is critical as the vulnerability is actively exploited.
- Action
- Apply the latest security patches for Microsoft Exchange Server.
AI-assisted analysis generated from the source advisory — verify against the original.
⚡ Watch Exchange Server
Get an email when a new Exchange Server advisory drops — max one per day, one-click unsubscribe.
Details
Original advisory: https://nvd.nist.gov/vuln/detail/CVE-2021-42321
Exploitation outlook
EPSS (FIRST.org) estimates each CVE’s probability of exploitation in the next 30 days — here is the CSIRTS.com read on those numbers.
- Exploitation confirmedCVE-2021-42321Already exploited in the wild (CISA KEV) — the prediction phase is over. Patch now. Riskier than 100% of all scored CVEs.
Referenced CVEs
| CVE | CSIRTS overview | External |
|---|---|---|
| CVE-2021-42321 | coverage & exploitation status | NVD · CVE.org |
Recent advisories for Microsoft Exchange Server
A cluster of recent advisories against the same product widens the attack surface — attackers routinely chain freshly published CVEs on one product, so review these together.
- highCVE-2026-45504: Microsoft Exchange Server Elevation of Privilege Vulnerabilitymsrc · 2026-06-09
- mediumCVE-2026-45502: Microsoft Exchange Server Information Disclosure Vulnerabilitymsrc · 2026-06-09
- highCVE-2026-45503: Microsoft Exchange Server Information Disclosure Vulnerabilitymsrc · 2026-06-09
- mediumCVE-2026-45500: Microsoft Exchange Server Spoofing Vulnerabilitymsrc · 2026-06-09
- mediumCVE-2026-45501: Microsoft Exchange Server Spoofing Vulnerabilitymsrc · 2026-06-09
- highCVE-2026-45583: Microsoft Exchange Server Remote Code Execution Vulnerabilitymsrc · 2026-06-09
More from CISA Known Exploited Vulnerabilities
- criticalCVE-2026-48939: iCagenda Unrestricted Upload of File with Dangerous Type Vulnerability2026-07-10
- criticalCVE-2026-56291: Balbooa Forms Unrestricted Upload of File with Dangerous Type Vulnerability2026-07-10
- criticalCVE-2026-48908: JoomShaper SP Page Builder Unrestricted Upload of File with Dangerous Type Vulnerability2026-07-07
- criticalCVE-2026-55255: Langflow Authorization Bypass Through User-Controlled Key Vulnerability2026-07-07
- criticalCVE-2026-48282: Adobe ColdFusion Path Traversal Vulnerability2026-07-07